Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Amine oxidase [flavin-containing] B' and Ligand = 'BDBM29143'
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))TBA
LigandPNGBDBM29143(CHEMBL7976 | Chalcone 1 | Chalcone, 13 | cid_63776...)copy SMILEScopy InChI
Affinity DataKi:  56nMAssay Description:Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI cells assessed as inhibition of H2O2 production using kynuramine as subst...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78K1CPubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))TBA
LigandPNGBDBM29143(CHEMBL7976 | Chalcone 1 | Chalcone, 13 | cid_63776...)copy SMILEScopy InChI
Affinity DataIC50: 1.41E+3nMpH: 7.4 T: 2°CAssay Description:The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63K8TPubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))TBA
LigandPNGBDBM29143(CHEMBL7976 | Chalcone 1 | Chalcone, 13 | cid_63776...)copy SMILEScopy InChI
Affinity DataIC50: 1.41E+6nMAssay Description:Inhibition of MAO-B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0JDCPubMed