Compile Data Set for Download or QSAR
Found 5 Enz. Inhib. hit(s) with Target = 'Amine oxidase [flavin-containing] B' and Ligand = 'BDBM50049240'
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Dart NeuroScience, LLC

Curated by ChEMBL
LigandPNGBDBM50049240((+-)-5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)m...)copy SMILEScopy InChI
Affinity DataKi:  199nMAssay Description:Inhibition of human recombinant soluble MAO-B expressed in Pichia pastoris incubated for 30 mins prior to substrate addition measured after 60 mins b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38V8KPubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Dart NeuroScience, LLC

Curated by ChEMBL
LigandPNGBDBM50049240((+-)-5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)m...)copy SMILEScopy InChI
Affinity DataKi:  271nMAssay Description:Inhibition of human recombinant microsomal MAO-B expressed in Pichia pastoris incubated for 30 mins prior to substrate addition measured after 60 min...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38V8KPubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Dart NeuroScience, LLC

Curated by ChEMBL
LigandPNGBDBM50049240((+-)-5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)m...)copy SMILEScopy InChI
Affinity DataKi:  500nMAssay Description:Competitive inhibition of human MAOB expressed in Pichia pastorisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3N7WPubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50049240((+-)-5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)m...)copy SMILEScopy InChI
Affinity DataKi:  2.10E+3nMAssay Description:Competitive inhibition of rat MAOB expressed in Pichia pastorisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3N7WPubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Dart NeuroScience, LLC

Curated by ChEMBL
LigandPNGBDBM50049240((+-)-5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)m...)copy SMILEScopy InChI
Affinity DataIC50: 298nMAssay Description:Inhibition of human recombinant MAO-B after 15 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46SX1PubMed