Compile Data Set for Download or QSAR
Found 8 Enz. Inhib. hit(s) with Target = 'Androgen receptor' and Ligand = 'BDBM50156506'
TargetAndrogen receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156506((1S,6S,7S)-4-(4-Cyano-3-trifluoromethyl-phenyl)-3,...)copy SMILEScopy InChI
Affinity DataKi:  40nMAssay Description:Displacement of [3H]-DHT from androgen receptor of human MDA-453 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1533WPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156506((1S,6S,7S)-4-(4-Cyano-3-trifluoromethyl-phenyl)-3,...)copy SMILEScopy InChI
Affinity DataKi:  40nMAssay Description:Displacement of [3H]DHT from human androgen receptor in MDA453 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5GGTPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156506((1S,6S,7S)-4-(4-Cyano-3-trifluoromethyl-phenyl)-3,...)copy SMILEScopy InChI
Affinity DataKi:  180nMAssay Description:Displacement of [3H]-DHT from androgen receptor of human MDA-453 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1533WPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156506((1S,6S,7S)-4-(4-Cyano-3-trifluoromethyl-phenyl)-3,...)copy SMILEScopy InChI
Affinity DataIC50: 640nMAssay Description:In vitro antagonistic activity against androgen receptor of MDA-453 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1533WPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156506((1S,6S,7S)-4-(4-Cyano-3-trifluoromethyl-phenyl)-3,...)copy SMILEScopy InChI
Affinity DataIC50: 770nMAssay Description:In vitro antagonistic activity against androgen receptor of MDA-453 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1533WPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156506((1S,6S,7S)-4-(4-Cyano-3-trifluoromethyl-phenyl)-3,...)copy SMILEScopy InChI
Affinity DataIC50: 774nMAssay Description:Antagonist activity at human androgen receptor in MDA453 cells by alkaline phosphatase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5GGTPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156506((1S,6S,7S)-4-(4-Cyano-3-trifluoromethyl-phenyl)-3,...)copy SMILEScopy InChI
Affinity DataIC50: 4.38E+3nMAssay Description:In vitro antagonistic activity against mutant androgen receptor of LNCap cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1533WPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156506((1S,6S,7S)-4-(4-Cyano-3-trifluoromethyl-phenyl)-3,...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:In vitro antagonistic activity against mutant androgen receptor of LNCap cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1533WPubMed