Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Apelin receptor' and Ligand = 'BDBM50244513'
TargetApelin receptor(Homo sapiens (Human))
Universit£ de Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50244513(CHEMBL4072080)copy SMILEScopy InChI
Affinity DataKi:  1.90nMAssay Description:Displacement of [125I]-[Nle75, Tyr77] Pyr1-apelin-13 from YFP-tagged human APJ receptor expressed in HEK293 cell membranes after 1 hr by gamma-counti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0BC2PubMed
TargetApelin receptor(Homo sapiens (Human))
Universit£ de Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50244513(CHEMBL4072080)copy SMILEScopy InChI
Affinity DataEC50:  9.20nMAssay Description:Activity at human APJ receptor expressed in HEK293 cells assessed as dissociation of Galphai1 from Gbetagamma subunit after 5 mins by BRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0BC2PubMed
TargetApelin receptor(Homo sapiens (Human))
Universit£ de Sherbrooke

Curated by ChEMBL
LigandPNGBDBM50244513(CHEMBL4072080)copy SMILEScopy InChI
Affinity DataEC50:  274nMAssay Description:Activity at GFP10-tagged human APJ receptor expressed in HEK293 cells assessed as induction of RlucII-tagged beta-arrestin-2 recruitment after 30 min...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0BC2PubMed