Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with Target = 'Apelin receptor' and Ligand = 'BDBM50544724'
TargetApelin receptor(Homo sapiens (Human))
RTI International

Curated by ChEMBL
LigandPNGBDBM50544724(CHEMBL4641469)copy SMILEScopy InChI
Affinity DataEC50:  2.47E+3nMAssay Description:Agonist activity at human APJ receptor stably expressed in CHOK1 cells assessed as induction of beta-arrestin 2 recruitment incubated for 90 mins by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MJXPubMed
TargetApelin receptor(Homo sapiens (Human))
RTI International

Curated by ChEMBL
LigandPNGBDBM50544724(CHEMBL4641469)copy SMILEScopy InChI
Affinity DataEC50:  424nMAssay Description:Agonist activity at human APJ receptor stably expressed in CHO cells co-expressing Galphaq16 assessed as increase in intracellular calcium mobilizati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MJXPubMed
TargetApelin receptor(Homo sapiens (Human))
RTI International

Curated by ChEMBL
LigandPNGBDBM50544724(CHEMBL4641469)copy SMILEScopy InChI
Affinity DataEC50:  424nMAssay Description:Agonist activity at Galphaq16-fused human APJ receptor expressed in CHO cells assessed as stimulation of Ca2+ mobilization incubated for 1 hr by Calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8RGNPubMed
TargetApelin receptor(Homo sapiens (Human))
RTI International

Curated by ChEMBL
LigandPNGBDBM50544724(CHEMBL4641469)copy SMILEScopy InChI
Affinity DataEC50:  238nMAssay Description:Agonist activity at human APJ receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 40 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8RGNPubMed
TargetApelin receptor(Homo sapiens (Human))
RTI International

Curated by ChEMBL
LigandPNGBDBM50544724(CHEMBL4641469)copy SMILEScopy InChI
Affinity DataEC50:  2.47E+3nMAssay Description:Agonist activity at human AGTRL1 expressed in CHO-K1 cells assessed as induction of beta-arrestin 2 recruitment incubated for 90 mins by PathHunter a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8RGNPubMed
TargetApelin receptor(Homo sapiens (Human))
RTI International

Curated by ChEMBL
LigandPNGBDBM50544724(CHEMBL4641469)copy SMILEScopy InChI
Affinity DataEC50:  238nMAssay Description:Agonist activity at human APJ receptor stably expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67MJXPubMed