Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Apoptosis regulator Bcl-2' and Ligand = 'BDBM145176'
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
AbbVie Inc.

US Patent
LigandPNGBDBM145176(US8952157, 367 | US9303025, 367)copy SMILEScopy InChI
Affinity DataKi:  0.0120nM ΔG°:  -62.3kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 μM (2× starting concentration; 10% DMSO) and 10 μ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XD10JPUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
AbbVie Inc.

US Patent
LigandPNGBDBM145176(US8952157, 367 | US9303025, 367)copy SMILEScopy InChI
Affinity DataKi:  0.0120nM ΔG°:  -62.3kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65G9US Patent