Compile Data Set for Download or QSAR
Found 7 Enz. Inhib. hit(s) with Target = 'Apoptosis regulator Bcl-2' and Ligand = 'BDBM50336576'
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Dalian University of Technology

Curated by ChEMBL
LigandPNGBDBM50336576(3-Thiomorpholin-8-oxo-8H-acenaphtho[1,2-b]pyrrole-...)copy SMILEScopy InChI
Affinity DataKi:  310nMAssay Description:Binding affinity to Bcl-2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RF5V96PubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Dalian University of Technology

Curated by ChEMBL
LigandPNGBDBM50336576(3-Thiomorpholin-8-oxo-8H-acenaphtho[1,2-b]pyrrole-...)copy SMILEScopy InChI
Affinity DataKi:  310nMAssay Description:Displacement of FAM-Bid peptide from human recombinant Bcl2 after 30 mins by by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6D8WPubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Dalian University of Technology

Curated by ChEMBL
LigandPNGBDBM50336576(3-Thiomorpholin-8-oxo-8H-acenaphtho[1,2-b]pyrrole-...)copy SMILEScopy InChI
Affinity DataKi:  310nMAssay Description:Binding affinity to Bcl-2 (unknown origin) fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2B7HPubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Dalian University of Technology

Curated by ChEMBL
LigandPNGBDBM50336576(3-Thiomorpholin-8-oxo-8H-acenaphtho[1,2-b]pyrrole-...)copy SMILEScopy InChI
Affinity DataKi:  319nMAssay Description:Displacement of FAM-Bid from human Bcl-2 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RF5V96PubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Dalian University of Technology

Curated by ChEMBL
LigandPNGBDBM50336576(3-Thiomorpholin-8-oxo-8H-acenaphtho[1,2-b]pyrrole-...)copy SMILEScopy InChI
Affinity DataIC50: 285nMAssay Description:Displacement of FAM-Bid from human recombinant Bcl-2 after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RF5V96PubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Dalian University of Technology

Curated by ChEMBL
LigandPNGBDBM50336576(3-Thiomorpholin-8-oxo-8H-acenaphtho[1,2-b]pyrrole-...)copy SMILEScopy InChI
Affinity DataIC50: 715nMAssay Description:Binding affinity to human Bcl-2 (unknown origin) by biotin-Bim displacement based ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2B7HPubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Dalian University of Technology

Curated by ChEMBL
LigandPNGBDBM50336576(3-Thiomorpholin-8-oxo-8H-acenaphtho[1,2-b]pyrrole-...)copy SMILEScopy InChI
Affinity DataKd:  310nMAssay Description:Inhibition of FAM-Bid binding to Bcl-2 (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZC85BPPubMed