Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Apoptosis regulator Bcl-2' and Ligand = 'BDBM53290'
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM53290(2-[4-[(4-bromophenyl)sulfonylamino]-1-hydroxynapht...)copy SMILEScopy InChI
Affinity DataKi:  2.90E+3nMAssay Description:Inhibition of 5-FAM-tagged Bid-BH3 peptide binding to Bcl2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765JNWPubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM53290(2-[4-[(4-bromophenyl)sulfonylamino]-1-hydroxynapht...)copy SMILEScopy InChI
Affinity DataKi:  1.10E+4nMAssay Description:Inhibition of Bcl2 (unknown origin) using 5-FAM-Bid-BH3 as substrate incubated for 30 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3QTBPubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM53290(2-[4-[(4-bromophenyl)sulfonylamino]-1-hydroxynapht...)copy SMILEScopy InChI
Affinity DataKi:  2.38E+4nMAssay Description:Displacement of Flu-BID/FAM-BID from His-tagged BCL2 (1 to 202) (unknown origin) expressed in Escherichia coli BL21(DE3) after 3 hrs by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20003NCPubMed