Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Apoptosis regulator Bcl-2' and Ligand = 'BDBM552934'
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))TBA
LigandPNGBDBM552934((R)-4-(4-((2-(3-chlorobicyclo[1.1.1]pentan-1-yl)-5...)copy SMILES
Affinity DataIC50: 10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QR51BHUS Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))TBA
LigandPNGBDBM552934((R)-4-(4-((2-(3-chlorobicyclo[1.1.1]pentan-1-yl)-5...)copy SMILES
Affinity DataIC50: 10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HD7ZW9US Patent