Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Arginase-1' and Ligand = 'BDBM50577458'
TargetArginase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50577458(CHEMBL4858437)copy SMILES
Affinity DataIC50: 16nMAssay Description:Inhibition of ARG1 (unknown origin) assessed as reduction in thio-ornithine production using thioarginine as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8XQ7PubMed
TargetArginase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50577458(CHEMBL4858437)copy SMILES
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant ARG1 expressed in Escherichia coli using thioarginine as a substrate preincubated for 30 mins followed by substrate a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542SD6PubMed
TargetArginase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50577458(CHEMBL4858437)copy SMILES
Affinity DataEC50:  3.40E+3nMAssay Description:Inhibition of human ARG1 in HEK293 cells by cell based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542SD6PubMed