Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Aromatase' and Ligand = 'BDBM50435003'
TargetAromatase(Homo sapiens (Human))
State University of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM50435003(ENDOXIFEN)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human placental microsomal aromatase using testosterone as substrate assessed as formation of estradiol after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7D2SPubMed
TargetAromatase(Homo sapiens (Human))
State University of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM50435003(ENDOXIFEN)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human recombinant placental aromataseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3GR5PubMed
TargetAromatase(Homo sapiens (Human))
State University of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM50435003(ENDOXIFEN)copy SMILEScopy InChI
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of recombinant human aromatase preincubated for 10 mins followed by substrate and beta-NADP+ addition and measured for 60 mins by fluoresc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542S0TPubMed
TargetAromatase(Homo sapiens (Human))
State University of New York Upstate Medical University

Curated by ChEMBL
LigandPNGBDBM50435003(ENDOXIFEN)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human aromatase assessed as reduction in fluorescence intensity preincubated with NADPH regenerating system for 10 mins followed by sub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76HFCPubMed