Compile Data Set for Download or QSAR
Found 52 Enz. Inhib. hit(s) with Target = 'Aromatase' and Ligand = 'BDBM9460'
TargetAromatase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataKi:  470nMAssay Description:Competitive inhibition of human placental Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SB46BPPubMedDrugBank
TargetAromatase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataKi:  600nMAssay Description:Inhibitory activity against human placental cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GM869QPubMedDrugBank
TargetAromatase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataKi:  600nMAssay Description:Inhibitory constant (Ki) for Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WM1FK8PubMedDrugBank
TargetAromatase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataKi:  600nMAssay Description:Binding affinity was measured on Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VM4CW9PubMedDrugBank
TargetAromatase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataKi:  680nMAssay Description:Inhibition of Cytochrome P450 19A1 against testosterone at 1.5 uM (Km=0.13 uM)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28051MGPubMedDrugBank
TargetAromatase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataKi:  1.41E+3nM ΔG°:  -34.7kJ/mole IC50: 2.80E+3nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0DCKPubMedDrugBank
TargetAromatase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataKi:  1.41E+3nM ΔG°:  -34.7kJ/mole IC50: 2.80E+3nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB154RPubMedDrugBank
TargetAromatase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataKi:  1.41E+3nM ΔG°:  -34.7kJ/mole IC50: 2.80E+3nMpH: 7.0 T: 2°CAssay Description:Inhibition of human placental aromatase was determined by monitoring the amount of 3H2O released as the enzyme converts [1beta-3H]androst-4-ene-3,17-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4GP7PubMedDrugBank
TargetAromatase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataKi:  1.80E+3nMAssay Description:Inhibition of human placental cytochrome P450 19A1 with testosteroneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154J7XPubMedDrugBank
TargetAromatase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataKi:  1.80E+3nMAssay Description:Inhibition of human placental cytochrome P450 19A1 with androstenedioneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GM869QPubMedDrugBank
TargetAromatase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataKi:  4.10E+3nMAssay Description:Inhibition of human aromatase extracted from placental microsomes using [1,2-3H]androstenedione as substrate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66NMZPubMedDrugBank
TargetAromatase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataIC50: 5.20nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8FFSPubMedDrugBank
TargetAromatase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:Aromatase inhibition was quantified by measuring the fluorescent intensity of fluorescein, the hydrolysis product of dibenzylfluorescein (DBF), by ar...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NP22RVPubMedDrugBank
TargetAromatase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:Inhibition of human aromataseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668F0ZPubMedDrugBank
TargetAromatase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human placental microsome cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SB46BPPubMedDrugBank
TargetAromatase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 AromataseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65RWPubMedDrugBank
TargetAromatase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:In vitro inhibition of human placental Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZK5FR9PubMedDrugBank
TargetAromatase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of aromatase activity in human placental microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0FHSPubMedDrugBank
TargetAromatase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataIC50: 5.20E+3nMAssay Description:In vitro inhibition of [1,2,6,7-3H]-androstenedione binding to human placental microsome cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125S01PubMedDrugBank
TargetAromatase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of aromatase in human placental microsomes assessed as inhibition of aromatization of [1,2,6,7-3H] androstenedione by flow scintillation a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90CBPubMedDrugBank
TargetAromatase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataIC50: 6.13E+3nMAssay Description:Inhibition of Cytochrome P450 19A1 against testosterone at 1.5 microM (Km=0.13 uM)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28051MGPubMedDrugBank
TargetAromatase(Rattus norvegicus)
Universität des Saarlandes

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataIC50: 6.20E+3nMAssay Description:In vitro inhibition of rat ovarian microsomal Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9H9SPubMed
TargetAromatase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of aromatase from human placental microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RB74C4PubMedDrugBank
TargetAromatase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of HIF-1alpha in human Hep3B cells cotransfected with pGL3-HRE-luciferase plasmid after 24 hrs by dual-luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0W5FPubMedDrugBank
TargetAromatase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of purified HIV-2 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9SH5PubMedDrugBank
TargetAromatase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibitory activity against human placental cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GM869QPubMedDrugBank
TargetAromatase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of Cytochrome P450 19A1 against Androstenedione at 0.25 uM (Km=55 nM)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28051MGPubMedDrugBank
TargetAromatase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of CYP19 in human placental microsome using [1beta-3H]-androstenedione as substrate after 15 mins in presence of NADPH by liquid scintilla...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9SH5PubMedDrugBank
TargetAromatase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human placental aromatase assessed as conversion of [1beta-3H]androstenedione to [1beta-3H]estrone after 20 mins by liquid scintillatio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2V58PubMedDrugBank
TargetAromatase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NP28CDPubMedDrugBank
TargetAromatase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human aromatase transfected in human MCF7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7D2SPubMedDrugBank
TargetAromatase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+4nMAssay Description:In vitro inhibition of aldosterone production in rat adrenal tissueMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QN65RWPubMedDrugBank
TargetAromatase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human placental cytochrome P450 19A1 with androstenedioneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GM869QPubMedDrugBank
TargetAromatase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataIC50: 1.85E+4nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta,2beta-3H]testosterone during aromatization. After incubation, the ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D21VTHPubMedDrugBank
TargetAromatase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataIC50: 1.85E+4nMT: 2°CAssay Description:The classical 3H2O assay was used to measure the effect of the inhibitor compounds on aromatase activity using human placental microsomes.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56H9ZPubMedDrugBank
TargetAromatase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataIC50: 1.85E+4nMAssay Description:Inhibition of human placental microsome cytochrome P450 19A1 aromataseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28S4P6HPubMedDrugBank
TargetAromatase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataIC50: 1.85E+4nMAssay Description:Inhibition of human placental aromatase, cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ8ZK7PubMedDrugBank
TargetAromatase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataIC50: 1.85E+4nMAssay Description:Inhibition of Human placental Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9H9SPubMedDrugBank
TargetAromatase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataIC50: 1.85E+4nMAssay Description:Inhibition of cytochrome P450 19A1 of human placental microsomes with [1beta,2beta-3H]testosteroneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GH9HB7PubMedDrugBank
TargetAromatase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataIC50: 2.85E+4nMAssay Description:Inhibition of aromatase in Homo sapiens (human) placental microsome assessed as tritiated H2O release from [1-beta-3H] androstenedione substrate prei...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB48NJDrugBank
TargetAromatase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataIC50: 2.85E+4nMAssay Description:Inhibition of Homo sapiens (human) aromatase assessed as 3H2O formation using [1beta,2beta-3H]testosterone as substrate by liquid scintillation count...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6TCNDrugBank
TargetAromatase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataIC50: 2.98E+4nMAssay Description:Inhibition of CYP19More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27TV6PubMedDrugBank
TargetAromatase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataIC50: 2.98E+4nMAssay Description:Inhibition of aromatase in human placental microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7VF7PubMedDrugBank
TargetAromatase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Cytochrome P450 19A1 in human placentaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z93WCPubMedDrugBank
TargetAromatase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:In vitro inhibition of cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SB46BPPubMedDrugBank
TargetAromatase(Rattus norvegicus)
Universität des Saarlandes

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of rat ovarian Cytochrome P450 19AMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ST7NT9PubMed
TargetAromatase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+4nMAssay Description:In vitro inhibitory concentration against human placental Cytochrome P450 19A was determined using [1beta,2beta-3H]testosterone as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ST7NT9PubMedDrugBank
TargetAromatase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of human placental aromataseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DR2THBPubMedDrugBank
TargetAromatase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+4nMAssay Description:In vitro inhibitory concentration against human placental Cytochrome P450 19A was determined using [1beta,2beta-3H]testosterone as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ST7NT9PubMedDrugBank
TargetAromatase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+4nMAssay Description:Concentration of the compound inhibiting AromataseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26972HSPubMedDrugBank
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