Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with Target = 'Aromatase' and Ligand = 'BDBM9475'
TargetAromatase(Homo sapiens (Human))
Universit£ degli Studi di Bari"Aldo Moro"

Curated by ChEMBL
LigandPNGBDBM9475(4-(1H-Imidazol-1-ylmethyl)-7-phenoxy-2H-chromen-2-...)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Inhibition of human placental microsomal CYP19 using [1beta-3H]androstenedione substrate pre-incubated for 5 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56MC3PubMed
TargetAromatase(Homo sapiens (Human))
Universit£ degli Studi di Bari"Aldo Moro"

Curated by ChEMBL
LigandPNGBDBM9475(4-(1H-Imidazol-1-ylmethyl)-7-phenoxy-2H-chromen-2-...)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibition of human placental microsome CYP19 using [1beta-3H] androstenedione as a substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X583QPubMed
TargetAromatase(Homo sapiens (Human))
Universit£ degli Studi di Bari"Aldo Moro"

Curated by ChEMBL
LigandPNGBDBM9475(4-(1H-Imidazol-1-ylmethyl)-7-phenoxy-2H-chromen-2-...)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibition of human aromatase-mediated conversion of [1beta3H]androstenedione to estrone by liquid scintillation counting in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ9080PubMed
TargetAromatase(Homo sapiens (Human))
Universit£ degli Studi di Bari"Aldo Moro"

Curated by ChEMBL
LigandPNGBDBM9475(4-(1H-Imidazol-1-ylmethyl)-7-phenoxy-2H-chromen-2-...)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibition of human placental microsomal aromatase using testosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z96V5PubMed
TargetAromatase(Homo sapiens (Human))
Universit£ degli Studi di Bari"Aldo Moro"

Curated by ChEMBL
LigandPNGBDBM9475(4-(1H-Imidazol-1-ylmethyl)-7-phenoxy-2H-chromen-2-...)copy SMILEScopy InChI
Affinity DataIC50: 51nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3R0CPubMed
TargetAromatase(Homo sapiens (Human))
Universit£ degli Studi di Bari"Aldo Moro"

Curated by ChEMBL
LigandPNGBDBM9475(4-(1H-Imidazol-1-ylmethyl)-7-phenoxy-2H-chromen-2-...)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibition of human placental aromatase in presence of [1beta,2beta-3H] testosterone by Thompson and Siiteri methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZC84Q6PubMed