Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Aurora kinase A' and Ligand = 'BDBM109209'
TargetAurora kinase A(Homo sapiens (Human))
University of Tartu, Ravila 14A, 50411 Tartu (Estonia)

LigandPNGBDBM109209(VX-689)copy SMILEScopy InChI
Affinity DataKi:  0.0155nM ΔG°:  -62.7kJ/mole IC50: 3.88nMT: 2°CAssay Description:Threefold dilution series of inhibitors in assay buffer were prepared in wells of a microtiter plate (final concentration stating from 2uM), and TAMR...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028Q58PubMed
TargetAurora kinase A(Homo sapiens (Human))
University of Tartu, Ravila 14A, 50411 Tartu (Estonia)

LigandPNGBDBM109209(VX-689)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMT: 2°CAssay Description:Threefold dilution series of inhibitors in assay buffer were prepared in wells of a microtiter plate (final concentration stating from 2uM). Subseque...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028Q58PubMed