Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Aurora kinase A' and Ligand = 'BDBM247371'
TargetAurora kinase A(Homo sapiens (Human))
CANCER RESEARCH TECHNOLOGY LIMITED

US Patent
LigandPNGBDBM247371(US9447092, 1)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Myc-tagged Aurora A was transfected in Hela cells using Lipofectamine LTX in 24 well plates, and 24 hours after transfection, cells were treated with...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6J9CUS Patent
TargetAurora kinase A(Homo sapiens (Human))
CANCER RESEARCH TECHNOLOGY LIMITED

US Patent
LigandPNGBDBM247371(US9447092, 1)copy SMILEScopy InChI
Affinity DataKd:  7.5nMAssay Description:The kinase selectivity was assessed by profiling Example 1 in a 442-kinase panel (386 non-mutant kinases) at a concentration of 1 μM using the K...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6J9CUS Patent