Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Aurora kinase A' and Ligand = 'BDBM50370442'
TargetAurora kinase A(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50370442(CHEMBL4175638)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of GST-tagged human recombinant Aurora A kinase domain (123 to 401 residues) expressed in Sf9 cells after 120 mins by kinase-glo luminesce...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D2216WPubMed
TargetAurora kinase A(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50370442(CHEMBL4175638)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of Aurora-A autophosphorylation at Thr288 in human HCT116 cells after 1 hr by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D2216WPubMed