Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with Target = 'B1 bradykinin receptor' and Ligand = 'BDBM50182221'
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50182221(CHEMBL381366 | N-((R)-6-((tert-butylamino)methyl)-...)copy SMILEScopy InChI
Affinity DataKi:  23nMAssay Description:Displacement of [3H]DAK from human bradykinin B1 receptor expressed in CHO-D-/aequorin cells by rapid filtration techniqueMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76CCTPubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50182221(CHEMBL381366 | N-((R)-6-((tert-butylamino)methyl)-...)copy SMILEScopy InChI
Affinity DataKi:  23nMAssay Description:Antagonist activity at human bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX79R6PubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50182221(CHEMBL381366 | N-((R)-6-((tert-butylamino)methyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Antagonist activity at human bradykinin B1 receptor expressed in CHO cells assessed as inhibition of agonist-induced calcium efflux by aquerin based ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX79R6PubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50182221(CHEMBL381366 | N-((R)-6-((tert-butylamino)methyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human B1 receptor by calcium influx functional assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN08K7PubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50182221(CHEMBL381366 | N-((R)-6-((tert-butylamino)methyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Antagonist activity at human bradykinin B1 receptor expressed in CHO-D-/aequorin cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76CCTPubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50182221(CHEMBL381366 | N-((R)-6-((tert-butylamino)methyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of human B1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN08K7PubMed