Compile Data Set for Download or QSAR
Found 8 Enz. Inhib. hit(s) with Target = 'B1 bradykinin receptor' and Ligand = 'BDBM50326709'
TargetB1 bradykinin receptor(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50326709((R)-1-(2-oxo-5-phenethyl-1-propyl-2,3-dihydro-1H-b...)copy SMILEScopy InChI
Affinity DataKi:  0.590nMAssay Description:Displacement of [3H]Lys0-des-Arg9-BK at human bradykinin B1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q289162ZPubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50326709((R)-1-(2-oxo-5-phenethyl-1-propyl-2,3-dihydro-1H-b...)copy SMILEScopy InChI
Affinity DataKi:  0.590nMAssay Description:Inhibition of human bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29P32C6PubMed
TargetB1 bradykinin receptor(RAT)
Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50326709((R)-1-(2-oxo-5-phenethyl-1-propyl-2,3-dihydro-1H-b...)copy SMILEScopy InChI
Affinity DataKi:  0.920nMAssay Description:Binding affinity to rat bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q289162ZPubMed
TargetB1 bradykinin receptor(RAT)
Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50326709((R)-1-(2-oxo-5-phenethyl-1-propyl-2,3-dihydro-1H-b...)copy SMILEScopy InChI
Affinity DataKi:  0.920nMAssay Description:Compound was tested for inhibition against rat Bradykinin receptor B1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29P32C6PubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50326709((R)-1-(2-oxo-5-phenethyl-1-propyl-2,3-dihydro-1H-b...)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Antagonist activity at human bradykinin B1 receptor in human MR5 cells assessed as [3H]inositol phosphate accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q289162ZPubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50326709((R)-1-(2-oxo-5-phenethyl-1-propyl-2,3-dihydro-1H-b...)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Compound was tested for inhibition against human bradykinin B1 receptor using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29P32C6PubMed
TargetB1 bradykinin receptor(RAT)
Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50326709((R)-1-(2-oxo-5-phenethyl-1-propyl-2,3-dihydro-1H-b...)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Compound was tested for inhibition against rat Bradykinin receptor B1 using FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29P32C6PubMed
TargetB1 bradykinin receptor(RAT)
Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50326709((R)-1-(2-oxo-5-phenethyl-1-propyl-2,3-dihydro-1H-b...)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Inhibition of rat bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q289162ZPubMed