Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with Target = 'B1 bradykinin receptor' and Ligand = 'BDBM50344100'
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50344100(2-((2R)-1-((4-methylphenyl)sulfonyl)-3-oxo-2-piper...)copy SMILEScopy InChI
Affinity DataKi:  0.100nMAssay Description:Antagonist activity at human B1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9WP1PubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50344100(2-((2R)-1-((4-methylphenyl)sulfonyl)-3-oxo-2-piper...)copy SMILEScopy InChI
Affinity DataKi:  0.160nMAssay Description:Antagonist activity at human bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX79R6PubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50344100(2-((2R)-1-((4-methylphenyl)sulfonyl)-3-oxo-2-piper...)copy SMILEScopy InChI
Affinity DataKi:  0.160nMAssay Description:Displacement of [3H]-DAK from human bradykinin B1 receptor expressed in CHO-D-/aequorin cells membrane after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6CB2PubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50344100(2-((2R)-1-((4-methylphenyl)sulfonyl)-3-oxo-2-piper...)copy SMILEScopy InChI
Affinity DataIC50: 0.220nMAssay Description:Antagonist activity at human bradykinin B1 receptor expressed in CHO cells assessed as inhibition of agonist-induced calcium efflux by aquerin based ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX79R6PubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50344100(2-((2R)-1-((4-methylphenyl)sulfonyl)-3-oxo-2-piper...)copy SMILEScopy InChI
Affinity DataIC50: 0.220nMAssay Description:Antagonist activity at human bradykinin B1 receptor expressed in CHO-D-/aequorin cells assessed as inhibition of DAK-induced intracellular calcium le...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6CB2PubMed
TargetB1 bradykinin receptor(Oryctolagus cuniculus)
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50344100(2-((2R)-1-((4-methylphenyl)sulfonyl)-3-oxo-2-piper...)copy SMILEScopy InChI
Affinity DataIC50: 4.10nMAssay Description:Inhibition of rabbit B1 receptor by cellular calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9WP1PubMed