Found 6 Enz. Inhib. hit(s) with Target = 'B2 bradykinin receptor' and Ligand = 'BDBM50409528' TargetB2 bradykinin receptor(Homo sapiens (Human))
Novartis Institute for Medical Sciences
Curated by ChEMBL
Novartis Institute for Medical Sciences
Curated by ChEMBL
Affinity DataKi: 2.79nMAssay Description:Displacement of [3H]BK (1 nM) from human Bradykinin receptor B2 expressed in Cos-7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 176nMAssay Description:Inhibition of specific binding of [3H]-BK (1 nM) to rat Bradykinin receptor B2 by 50% in NG108-15 cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of Bradykinin receptor B2-mediated contractions of rat uterus smooth muscleMore data for this Ligand-Target Pair
TargetB2 bradykinin receptor(Homo sapiens (Human))
Novartis Institute for Medical Sciences
Curated by ChEMBL
Novartis Institute for Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Antagonism of the [Ca2+] efflux actions of the human Bradykinin receptor B2 (SK-N-SH neuroblastoma)More data for this Ligand-Target Pair
TargetB2 bradykinin receptor(Homo sapiens (Human))
Novartis Institute for Medical Sciences
Curated by ChEMBL
Novartis Institute for Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:Antagonism of the [Ca2+] efflux actions of the human Bradykinin receptor B2 (WI38 fibroblasts)More data for this Ligand-Target Pair
Affinity DataIC50: 141nMAssay Description:Inhibition of increase in [Ca2+] efflux from NG108-15 cells caused by activation of rat Bradykinin receptor B2More data for this Ligand-Target Pair
