Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'BDNF/NT-3 growth factors receptor' and Ligand = 'BDBM50525709'
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
Zoetis

Curated by ChEMBL
LigandPNGBDBM50525709(CHEMBL4555143)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of inactive recombinant human His-tagged TrkB expressed in baculovirus expression system preincubated for 20 mins followed by ATP/SRCtide ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7M2BPubMed
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
Zoetis

Curated by ChEMBL
LigandPNGBDBM50525709(CHEMBL4555143)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant full length human TrkB transfected in CHO cells assessed as inhibition of NGF-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7M2BPubMed
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
Zoetis

Curated by ChEMBL
LigandPNGBDBM50525709(CHEMBL4555143)copy SMILEScopy InChI
Affinity DataKd:  1.70nMAssay Description:Binding affinity to recombinant human biotinylated and N-terminal DYKDDDDK-tagged TrkB kinase domain (456-822 residues) expressed in sf21 cells asses...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7M2BPubMed