Compile Data Set for Download or QSAR
Found 7 Enz. Inhib. hit(s) with Target = 'Beta-1 adrenergic receptor' and Ligand = 'BDBM50318159'
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50318159(8-Hydroxy-5-[(R)-1-hydroxy-2-(5,6-diethylindan-2-y...)copy SMILEScopy InChI
Affinity DataKi:  91nMAssay Description:Displacement of [125I]iodo-(+/-)-cyanopindolol from human adrenergic beta1 receptor expressed in CHO cells after 3 hrs by radio-ligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z89F2RPubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50318159(8-Hydroxy-5-[(R)-1-hydroxy-2-(5,6-diethylindan-2-y...)copy SMILEScopy InChI
Affinity DataKi:  91nMAssay Description:Displacement of [3H]CGP12177 from human beta-1 adrenoceptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7VVMPubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50318159(8-Hydroxy-5-[(R)-1-hydroxy-2-(5,6-diethylindan-2-y...)copy SMILEScopy InChI
Affinity DataKi:  180nMAssay Description:Binding affinity to human beta1-adrenoceptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73G09PubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50318159(8-Hydroxy-5-[(R)-1-hydroxy-2-(5,6-diethylindan-2-y...)copy SMILEScopy InChI
Affinity DataIC50: 316nMAssay Description:Binding affinity to adrenergic beta1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3NS2PubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50318159(8-Hydroxy-5-[(R)-1-hydroxy-2-(5,6-diethylindan-2-y...)copy SMILEScopy InChI
Affinity DataIC50: 316nMAssay Description:Binding affinity to beta1 adrenoceptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5H90PubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50318159(8-Hydroxy-5-[(R)-1-hydroxy-2-(5,6-diethylindan-2-y...)copy SMILEScopy InChI
Affinity DataEC50:  40nMAssay Description:Agonist activity at adrenergic beta1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3NS2PubMed
TargetBeta-1 adrenergic receptor(Rattus norvegicus (Rat))
Rhône-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50318159(8-Hydroxy-5-[(R)-1-hydroxy-2-(5,6-diethylindan-2-y...)copy SMILEScopy InChI
Affinity DataEC50:  2.31E+3nMAssay Description:Agonist activity at beta1 adrenoreceptor in rat left atria assessed as induction of ionotropic effectMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W09668PubMed