Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM150709'
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

LigandPNGBDBM150709(US8981112, 16 | US9526727, 16 | US9949975, Example...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Assay 1:The assay was performed in the presence of OptiMEM (supernatant collected over 24 h and cleared from cellular debris by centrifugation) conta...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25D8V5XUS Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

LigandPNGBDBM150709(US8981112, 16 | US9526727, 16 | US9949975, Example...)copy SMILEScopy InChI
Affinity DataIC50: 11nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56HG6US Patent