Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM16754'
TargetBeta-secretase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM16754(2-[2-(adamantan-1-yl)-5-phenyl-1H-pyrrol-1-yl]-N-[...)copy SMILEScopy InChI
Affinity DataIC50: 239nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7PK8PubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM16754(2-[2-(adamantan-1-yl)-5-phenyl-1H-pyrrol-1-yl]-N-[...)copy SMILEScopy InChI
Affinity DataIC50: 240nMpH: 4.5 T: 2°CAssay Description:A homogenous, continuous fluorescence resonance energy transfer (FRET) assay was used to assess compound inhibition of enzyme based on the cleavage o...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M043NGPubMed