Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM50398864'
TargetBeta-secretase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandPNGBDBM50398864(CHEMBL2178164)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3M8MPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandPNGBDBM50398864(CHEMBL2178164)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of BACE1 in human KBV1 cells expressing APP 751 Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production after overnight...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3M8MPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandPNGBDBM50398864(CHEMBL2178164)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of BACE1 in human HEK293 cells expressing APP 695 Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production after overnig...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3M8MPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandPNGBDBM50398864(CHEMBL2178164)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of BACE1 in human KBV1 cells expressing APP 751 Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production after overnight...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3M8MPubMed