Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM50419871'
TargetBeta-secretase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50419871(CHEMBL1957483)copy SMILEScopy InChI
Affinity DataIC50: 7.90nMAssay Description:Inhibition of BACE-1-mediated sAPPbeta production in human SH-SY5Y cells after 16 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60Q93PubMed
TargetBeta-secretase 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50419871(CHEMBL1957483)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of human BACE-1 using (Eu)CEVNLDAEFK(Qsy7) as substrate preincubated for 10 mins prior substrate addition measured after 15 mins by FRET-b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60Q93PubMed