Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Bifunctional dihydrofolate reductase-thymidylate synthase' and Ligand = 'BDBM50058024'
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Cryptosporidium hominis)
Yale University

Curated by ChEMBL
LigandPNGBDBM50058024(CHEMBL2426247)copy SMILEScopy InChI
Affinity DataIC50: 49nMAssay Description:Inhibition of DHFR activity of Cryptosporidium hominis bifunctional dihydrofolate reductase-thymidylate synthase assessed as reduction in NADPH oxida...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69M7FPubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Cryptosporidium hominis)
Yale University

Curated by ChEMBL
LigandPNGBDBM50058024(CHEMBL2426247)copy SMILEScopy InChI
Affinity DataIC50: 380nMAssay Description:Inhibition of thymidylate synthase activity of Cryptosporidium hominis bifunctional dihydrofolate reductase-thymidylate synthase assessed as reductio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69M7FPubMed