Found 4 Enz. Inhib. hit(s) with Target = 'Bifunctional ligase/repressor BirA' and Ligand = 'BDBM161470' TargetBifunctional ligase/repressor BirA(Staphylococcus aureus)
Monash University; Adelaide Research & Innovation Pty Ltd
US Patent
Monash University; Adelaide Research & Innovation Pty Ltd
US Patent
Affinity DataKi: 660nM ΔG°: -36.7kJ/mole IC50: 4.00E+3nMpH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
3D Structure (crystal)TargetBifunctional ligase/repressor BirA(Staphylococcus aureus)
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataKi: 660nMAssay Description:Inhibition of Staphylococcus aureus biotin protein ligase by LC/MS-SIM analysisMore data for this Ligand-Target Pair
TargetBifunctional ligase/repressor BirA(Escherichia coli)
Monash University; Adelaide Research & Innovation Pty Ltd
US Patent
Monash University; Adelaide Research & Innovation Pty Ltd
US Patent
Affinity DataKi: >3.00E+4nM ΔG°: >-26.9kJ/molepH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
TargetBifunctional ligase/repressor BirA(Escherichia coli)
Monash University; Adelaide Research & Innovation Pty Ltd
US Patent
Monash University; Adelaide Research & Innovation Pty Ltd
US Patent
Affinity DataKi: >3.00E+4nM ΔG°: >-26.9kJ/molepH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
