Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Bile acid receptor' and Ligand = 'BDBM50185707'
TargetBile acid receptor(Homo sapiens (Human))
Phenex Pharmaceuticals AG

Curated by ChEMBL
LigandPNGBDBM50185707(CHEMBL3822773)copy SMILEScopy InChI
Affinity DataEC50:  186nMAssay Description:Agonist activity at C-terminal Gal4-tagged human FXR (187 to 472 residues) expressed in HEK-293 cells co-expressing pFRluc by mammalian one hybrid as...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24ZB9PubMed
TargetBile acid receptor(Homo sapiens (Human))
Phenex Pharmaceuticals AG

Curated by ChEMBL
LigandPNGBDBM50185707(CHEMBL3822773)copy SMILEScopy InChI
Affinity DataEC50:  209nMAssay Description:Agonist activity at FXR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5JXGPubMed
TargetBile acid receptor(Homo sapiens (Human))
Phenex Pharmaceuticals AG

Curated by ChEMBL
LigandPNGBDBM50185707(CHEMBL3822773)copy SMILEScopy InChI
Affinity DataEC50:  4nMAssay Description:Agonist activity at FXR (unknown origin) by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5JXGPubMed
TargetBile acid receptor(Homo sapiens (Human))
Phenex Pharmaceuticals AG

Curated by ChEMBL
LigandPNGBDBM50185707(CHEMBL3822773)copy SMILEScopy InChI
Affinity DataEC50:  186nMAssay Description:Agonist activity at C-terminal Gal4-tagged human FXR (187 to 472 residues) expressed in HEK-293 cells co-expressing pFRluc by mammalian one hybrid as...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24ZB9PubMed