Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Bile acid receptor' and Ligand = 'BDBM50323522'
TargetBile acid receptor(Homo sapiens (Human))
Phenex Pharmaceuticals AG

Curated by ChEMBL
LigandPNGBDBM50323522(3-(2,6-dichlorophenyl)-5-isopropyl-4-((4-methylqui...)copy SMILEScopy InChI
Affinity DataEC50:  536nMAssay Description:Agonist activity at human GST-fused FXR LBD expressed in HEK293 cells coexpressing GAL4-DNA bindig domain and pFRluc by mammalian one-hybrid assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5F52PubMed
TargetBile acid receptor(Homo sapiens (Human))
Phenex Pharmaceuticals AG

Curated by ChEMBL
LigandPNGBDBM50323522(3-(2,6-dichlorophenyl)-5-isopropyl-4-((4-methylqui...)copy SMILEScopy InChI
Affinity DataEC50:  147nMAssay Description:Agonist activity at human GST-fused FXR LBD expressed in HEK293 cells coexpressing GAL4-DNA bindig domain and pFRluc by mammalian one-hybrid assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5F52PubMed
TargetBile acid receptor(Homo sapiens (Human))
Phenex Pharmaceuticals AG

Curated by ChEMBL
LigandPNGBDBM50323522(3-(2,6-dichlorophenyl)-5-isopropyl-4-((4-methylqui...)copy SMILEScopy InChI
Affinity DataEC50:  878nMAssay Description:Agonist activity at human full length FXR transfected in HEK293 cells coexpressing pTRexDest/pGL2promotor assessed as luciferase activity by direct r...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5F52PubMed