Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Bile acid receptor' and Ligand = 'BDBM50463011'
TargetBile acid receptor(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50463011(CHEMBL4241985)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Antagonist activity at full length human FXR expressed in HeLa cells co-expressing BSEP-pGL3/pSG5-hRXR after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8VTFPubMed
TargetBile acid receptor(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50463011(CHEMBL4241985)copy SMILEScopy InChI
Affinity DataIC50: 9.20nMAssay Description:Antagonist activity at full length human FXR expressed in HeLa cells co-expressing BSEP-pGL3/pSG5-hRXR assessed as inhibition of GW4064-induced recep...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8VTFPubMed