Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Bile salt export pump' and Ligand = 'BDBM82258'
TargetBile salt export pump(Homo sapiens (Human))TBA
LigandPNGBDBM82258(CAS_114798-26-4 | Losartan | NSC_3961)copy SMILEScopy InChI
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of human BSEP expressed in HEK293 cell membrane vesicles assessed as reduction in 3H-TCA uptake incubated for 5 mins by radiodetection met...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3JZPPubMed
TargetBile salt export pump(Homo sapiens (Human))TBA
LigandPNGBDBM82258(CAS_114798-26-4 | Losartan | NSC_3961)copy SMILEScopy InChI
Affinity DataIC50: 8.53E+3nMAssay Description:Ability to inhibit the binding of [125I]RT155 to Serotonin transporter in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TF00N2PubMed
TargetBile salt export pump(Homo sapiens (Human))TBA
LigandPNGBDBM82258(CAS_114798-26-4 | Losartan | NSC_3961)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP488MPubMed