Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Broad substrate specificity ATP-binding cassette transporter ABCG2' and Ligand = 'BDBM32617'
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent
LigandPNGBDBM32617(Botryllamide A, 1 | US8470888, Botryllamide A)copy SMILEScopy InChI
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition assay using ABCG2 or BCRP1.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RR1WWTUS Patent
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent
LigandPNGBDBM32617(Botryllamide A, 1 | US8470888, Botryllamide A)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition assay using ABCG2 or BCRP1.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RR1WWTUS Patent
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
The United States of America, as represented by the Secretary, Department of Health and Human Services

US Patent
LigandPNGBDBM32617(Botryllamide A, 1 | US8470888, Botryllamide A)copy SMILEScopy InChI
Affinity DataIC50: 3.34E+4nMpH: 7.4 T: 2°CAssay Description:IC50 and maximal activities for inhibition of PhA accumulation were determined from dose-response curves. The accumulation of PhA, a fluorescent ABCG...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542KZWPubMed