Found 11 Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4' and Ligand = 'BDBM50210164' TargetBromodomain-containing protein 4(Homo sapiens (Human))
Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of human His-tagged Brd4 bromodomain 2 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of [3H]-Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranesMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant human BRD4 bromodomain-1 (342 to 460 residues) expressed in Escherichia coli expression system after 120 mins by TR-FRET as...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of human His-tagged Brd4 bromodomain 1 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of N-terminal 6His-tagged human BRD4 bromodomain 1 (44 to 168 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated histon...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Affinity DataIC50: 73nMAssay Description:Inhibition of His/thioredoxin-tagged human recombinant BRD4 bromodomain-1 (43 to 166 residues) expressed in Escherichia coli BL21 Star (DE3) pre-incu...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Affinity DataIC50: 76nMAssay Description:Inhibition of recombinant human BRD4 bromodomain-1 (49 to 170 residues) expressed in Escherichia coli expression system after 120 mins by TR-FRET ass...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Affinity DataIC50: 77nMAssay Description:Inhibition of binding of a tetra-acetylated histone H4 peptide to His-tagged human BRD4(D1) expressed in bacteriaMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
Walter and Eliza Hall Institute of Medical Research
Curated by ChEMBL
