Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4' and Ligand = 'BDBM50578801'
TargetBromodomain-containing protein 4(Homo sapiens (Human))TBA
LigandPNGBDBM50578801(CHEMBL4862592)copy SMILES
Affinity DataIC50: 40nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from recombinant human N-terminal 6His-tagged BRD4-BD1 Y390A mutant (1 to 477 residue) expressed in E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9N20PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))TBA
LigandPNGBDBM50578801(CHEMBL4862592)copy SMILES
Affinity DataIC50: 40nMAssay Description:Inhibition of BRD4 in human PBMC assessed as reduction in LPS-induced IL-6 secretion incubated for 18 to 24 hrs by MSD assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9N20PubMed