Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 2' and Ligand = 'BDBM50231615'
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50231615((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-isopr...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Antagonist activity at CCR2 receptor in human monocytes assessed as inhibition of MCP1-mediated chemotaxisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ9046PubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50231615((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-isopr...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor in human monocytesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ9046PubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50231615((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-isopr...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor in human monocytesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ9046PubMed