Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 2' and Ligand = 'BDBM50257992'
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50257992((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-3-(2,3-...)copy SMILEScopy InChI
Affinity DataKi:  50nMAssay Description:Displacement of 0.1 nM [125I]CCL2 from human CCR2 expressing human U2OS cell membrane by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M67DXPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50257992((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-3-(2,3-...)copy SMILEScopy InChI
Affinity DataIC50: 77nMAssay Description:Antagonist activity at CCR2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20R9S95
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50257992((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-3-(2,3-...)copy SMILEScopy InChI
Affinity DataIC50: 77nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed