Found 4 Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 5' and Ligand = 'BDBM50336346' TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Antagonist activity at human CCR5 expressed in CHO cells assessed as inhibition of MIP-1alpha-induced calcium mobilization Ca assayMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 182nMAssay Description:Antagonist activity at human CCR5 expressed in HOS cells assessed as inhibition of cell fusion with HIV gp120 expressing HEK293 cells by LTR lucifera...More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 4.40E+4nMAssay Description:Antagonist activity at human CCR5 expressed in CHO cells assessed as inhibition of MIP-1alpha-induced calcium mobilizationMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 1.82E+5nMAssay Description:Antagonist activity against human CCR5 receptor assessed as inhibition of HIV1 gp120-induced cell-cell fusion between viral envolop protein expressin...More data for this Ligand-Target Pair
