Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'C-X-C chemokine receptor type 3' and Ligand = 'BDBM50211130'
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50211130((R)-N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydroquin...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1SXNPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50211130((R)-N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydroquin...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Displacement of [125I]-1P10 from human CXCR3 expressed in PBMC after 2 hrs in RPMI buffer by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX79KZPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50211130((R)-N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydroquin...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Antagonist activity against human CXCR3 expressed in human PBMC assessed as inhibition of cell migration in response to ITAC in plasmaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX79KZPubMed