Found 8 Enz. Inhib. hit(s) with Target = 'C5a anaphylatoxin chemotactic receptor 1' and Ligand = 'BDBM50111445' TargetC5a anaphylatoxin chemotactic receptor 1(Homo sapiens (Human))
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Displacement of [125I-C5a] from C5a receptor in human PBMC by scintillation countingMore data for this Ligand-Target Pair
TargetC5a anaphylatoxin chemotactic receptor 1(Homo sapiens (Human))
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Displacement of [125I-C5a] from C5a receptor in human PBMC by scintillation countingMore data for this Ligand-Target Pair
TargetC5a anaphylatoxin chemotactic receptor 1(Homo sapiens (Human))
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Antagonist activity at C5aR1 in HMDMMore data for this Ligand-Target Pair
TargetC5a anaphylatoxin chemotactic receptor 1(Homo sapiens (Human))
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Antagonist activity at human C5aR in CD88 transfected RBL cells assessed as inhibition of C5a-induced glucosaminidase releaseMore data for this Ligand-Target Pair
TargetC5a anaphylatoxin chemotactic receptor 1(Homo sapiens (Human))
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Antagonist activity at C5aR1 in human PMNMore data for this Ligand-Target Pair
TargetC5a anaphylatoxin chemotactic receptor 1(Homo sapiens (Human))
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Antagonist activity at human C5aR expressed in human PMN cells assessed as inhibition of glucosaminidase releaseMore data for this Ligand-Target Pair
TargetC5a anaphylatoxin chemotactic receptor 1(Homo sapiens (Human))
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataIC50: 104nMAssay Description:Inhibition of C5a binding to human C5aR expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetC5a anaphylatoxin chemotactic receptor 1(Homo sapiens (Human))
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Antagonist activity against the C5a receptorMore data for this Ligand-Target Pair
