Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'COP9 signalosome complex subunit 5' and Ligand = 'BDBM224012'
TargetCOP9 signalosome complex subunit 5(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM224012(Capzimin | US10005735, Compound 12)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:In brief, this Rpn11 bioassay employs a fluorescent polarization readout based on the ability of the 26S proteasome to cleave the protein substrate i...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22R3V09US Patent
TargetCOP9 signalosome complex subunit 5(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM224012(Capzimin | US10005735, Compound 12)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMpH: 7.5Assay Description:Csn5 activity was measured using purified CSN complex and the fluorescent substrate OGNedd8–SCFSkp2, in which a unique cysteine engineered into ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0D0BPubMed