Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Calcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1' and Ligand = 'BDBM50217498'
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50217498((R,Z)-N-(1-isopropyl-2-oxo-5-phenyl-2,3-dihydro-1H...)copy SMILEScopy InChI
Affinity DataKi:  55nMAssay Description:Displacement of [125I]CGRP from human CL receptor in RAMP1 membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9Q4DPubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50217498((R,Z)-N-(1-isopropyl-2-oxo-5-phenyl-2,3-dihydro-1H...)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Antagonist activity at human CGRP receptor in E10 cells assessed as inhibition of cAMP productionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9Q4DPubMed