Compile Data Set for Download or QSAR
Found 5 Enz. Inhib. hit(s) with Target = 'Calcitonin gene-related peptide type 1 receptor' and Ligand = 'BDBM50192559'
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck& Co

Curated by ChEMBL
LigandPNGBDBM50192559((R)-4-(2-oxo-2,3-dihydroimidazo[4,5-b]pyridin-1-yl...)copy SMILEScopy InChI
Affinity DataKi:  22nMAssay Description:Displacement of [125I]hCGRP from human CGRP receptor expressed in HEK293 cells coexpressing RAMP1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1XSKPubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck& Co

Curated by ChEMBL
LigandPNGBDBM50192559((R)-4-(2-oxo-2,3-dihydroimidazo[4,5-b]pyridin-1-yl...)copy SMILEScopy InChI
Affinity DataKi:  23nMAssay Description:Displacement of [125I]CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1QNXPubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck& Co

Curated by ChEMBL
LigandPNGBDBM50192559((R)-4-(2-oxo-2,3-dihydroimidazo[4,5-b]pyridin-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 49nMAssay Description:Activity at CGRP receptor assessed as inhibition of CGRP-stimulated cAMP productionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1QNXPubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck& Co

Curated by ChEMBL
LigandPNGBDBM50192559((R)-4-(2-oxo-2,3-dihydroimidazo[4,5-b]pyridin-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 49nMAssay Description:Antagonistic activity at human CGRP receptor expressed in HEK293 cells coexpressing RAMP1 assessed as inhibition of CGRP-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1XSKPubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck& Co

Curated by ChEMBL
LigandPNGBDBM50192559((R)-4-(2-oxo-2,3-dihydroimidazo[4,5-b]pyridin-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 730nMAssay Description:Antagonistic activity at human CGRP receptor expressed in HEK293 cells coexpressing RAMP1 assessed as inhibition of CGRP-induced cAMP production in p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1XSKPubMed