Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Calcitonin gene-related peptide type 1 receptor' and Ligand = 'BDBM50255035'
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck& Co

Curated by ChEMBL
LigandPNGBDBM50255035((S)-N-(2'-oxo-1,1',2',3-tetrahydrospiro[indene-2,3...)copy SMILEScopy InChI
Affinity DataKi:  2.30nMAssay Description:Displacement of [125I]hCGRP from human CGRP receptor expressed in HEK293 cells coexpressing RAMP1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1XSKPubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck& Co

Curated by ChEMBL
LigandPNGBDBM50255035((S)-N-(2'-oxo-1,1',2',3-tetrahydrospiro[indene-2,3...)copy SMILEScopy InChI
Affinity DataIC50: 8.60nMAssay Description:Antagonistic activity at human CGRP receptor expressed in HEK293 cells coexpressing RAMP1 assessed as inhibition of CGRP-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1XSKPubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck& Co

Curated by ChEMBL
LigandPNGBDBM50255035((S)-N-(2'-oxo-1,1',2',3-tetrahydrospiro[indene-2,3...)copy SMILEScopy InChI
Affinity DataIC50: 420nMAssay Description:Antagonistic activity at human CGRP receptor expressed in HEK293 cells coexpressing RAMP1 assessed as inhibition of CGRP-induced cAMP production in p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1XSKPubMed