Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Calcium/calmodulin-dependent protein kinase kinase 2' and Ligand = 'BDBM317462'
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM317462(4-(4-(cyclopentyloxy)-5-(2- methylbenzo[d]oxazol-6...)copy SMILEScopy InChI
Affinity DataIC50: 680nMAssay Description:Inhibition of CAMKK2 in human HCT116 cell lysate after 1 hr by LC-MS/MS analysis relative to controlMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0WX9PubMed
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Celgene Corporation

Curated by ChEMBL
LigandPNGBDBM317462(4-(4-(cyclopentyloxy)-5-(2- methylbenzo[d]oxazol-6...)copy SMILEScopy InChI
Affinity DataIC50: 728nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VQ34R8US Patent