Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Calcium/calmodulin-dependent protein kinase kinase 2' and Ligand = 'BDBM50271744'
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50271744(CHEMBL4128939)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of full-length human GST-tagged CAMKK2 using 5FAM-AKPKGNKDYHLQTCCGSLAYRRR-amide as substrate preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2DFBPubMed
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Mus musculus)
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50271744(CHEMBL4128939)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of CAMKK2 in mouse N39 cells assessed as decrease in AMPKalpha phosphorylation at T172 preincubated for 80 mins followed by inomycin addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2DFBPubMed