Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Cannabinoid receptor 1' and Ligand = 'BDBM29061'
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM29061(CHEMBL201602 | pyrazolopyrimidinone-based antagoni...)copy SMILEScopy InChI
Affinity DataKi:  0.600nM ΔG°:  -53.5kJ/mole EC50:  1nMpH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47MGDPubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM29061(CHEMBL201602 | pyrazolopyrimidinone-based antagoni...)copy SMILEScopy InChI
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]SR141716 from human CB1 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM79PMPubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM29061(CHEMBL201602 | pyrazolopyrimidinone-based antagoni...)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Functional activity at human CB1 receptor transfected in CHOK1 cells by [35SGTP]gammaS assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM79PMPubMed