Compile Data Set for Download or QSAR
Found 5 Enz. Inhib. hit(s) with Target = 'Cannabinoid receptor 1' and Ligand = 'BDBM50586724'
TargetCannabinoid receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50586724(CHEMBL5082666)copy SMILES
Affinity DataKi:  43nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in CHO-K1 cell membranes incubated for 60 mins by liquid scintillation spectrometry ana...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5S30PubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50586724(CHEMBL5082666)copy SMILES
Affinity DataEC50:  320nMAssay Description:Positive allosteric modulation of human CB1 receptor expressed in CHO-K1 cells assessed as beta-arrestin 2 recruitment incubated for 90 mins by PathH...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5S30PubMed
TargetCannabinoid receptor 1(Mus musculus (Mouse))TBA
LigandPNGBDBM50586724(CHEMBL5082666)copy SMILES
Affinity DataEC50:  30nMAssay Description:Positive allosteric modulation of CB1 receptor in MF1 mouse vas deferens assessed as inhibition of AEA-induced electrically evoked vas deferens contr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5S30PubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50586724(CHEMBL5082666)copy SMILES
Affinity DataEC50:  130nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO cell membranes assessed as increase in [35S]GTPgammaS binding incubated for 30 mins by liquid...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5S30PubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50586724(CHEMBL5082666)copy SMILES
Affinity DataEC50:  87nMAssay Description:Positive allosteric modulation of human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP production incubated ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5S30PubMed