Compile Data Set for Download or QSAR
Found 13 Enz. Inhib. hit(s) with Target = 'Cannabinoid receptor 2' and Ligand = 'BDBM50211843'
TargetCannabinoid receptor 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50211843(2-(2,4-dichlorophenylamino)-4-trifluoromethyl-pyri...)copy SMILEScopy InChI
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]CP55940 form human CB2 receptor transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K937DDPubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50211843(2-(2,4-dichlorophenylamino)-4-trifluoromethyl-pyri...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]Win55212 form human CB2 receptor transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K937DDPubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50211843(2-(2,4-dichlorophenylamino)-4-trifluoromethyl-pyri...)copy SMILEScopy InChI
Affinity DataEC50:  63nMAssay Description:Agonist activity at human recombinant CB2 receptor expressed in Saccharomyces cerevisiae cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W095M7PubMed
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50211843(2-(2,4-dichlorophenylamino)-4-trifluoromethyl-pyri...)copy SMILEScopy InChI
Affinity DataEC50:  91nMAssay Description:Agonist activity at rat CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W095M7PubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50211843(2-(2,4-dichlorophenylamino)-4-trifluoromethyl-pyri...)copy SMILEScopy InChI
Affinity DataEC50:  63nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP levelMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92B1FPubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50211843(2-(2,4-dichlorophenylamino)-4-trifluoromethyl-pyri...)copy SMILEScopy InChI
Affinity DataEC50:  350nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP releaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K937DDPubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50211843(2-(2,4-dichlorophenylamino)-4-trifluoromethyl-pyri...)copy SMILEScopy InChI
Affinity DataEC50:  431nMAssay Description:Agonist activity at CB2 receptor (unknown origin) expressed in CHO cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P626SPubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50211843(2-(2,4-dichlorophenylamino)-4-trifluoromethyl-pyri...)copy SMILEScopy InChI
Affinity DataEC50:  63nMAssay Description:Agonist activity at human recombinant cannabinoid CB2 receptor expressed in MMY23 Saccharomyces cerevisiae assessed as degradation of FDGlu to fluore...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20R9PG5PubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50211843(2-(2,4-dichlorophenylamino)-4-trifluoromethyl-pyri...)copy SMILEScopy InChI
Affinity DataEC50:  50nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ33M2PubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50211843(2-(2,4-dichlorophenylamino)-4-trifluoromethyl-pyri...)copy SMILEScopy InChI
Affinity DataEC50:  50nMAssay Description:Agonist activity at CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q208665CPubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50211843(2-(2,4-dichlorophenylamino)-4-trifluoromethyl-pyri...)copy SMILEScopy InChI
Affinity DataEC50:  343nMAssay Description:Agonist activity at CB2 receptor (unknown origin) expressed in CHO cells assessed as induction of calcium mobilization by fluo-4 AM dye-based fluores...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736TDDPubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50211843(2-(2,4-dichlorophenylamino)-4-trifluoromethyl-pyri...)copy SMILEScopy InChI
Affinity DataEC50:  437nMAssay Description:Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z039X8PubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50211843(2-(2,4-dichlorophenylamino)-4-trifluoromethyl-pyri...)copy SMILEScopy InChI
Affinity DataEC50:  343nMAssay Description:Agonist activity at CB2 receptor (unknown origin) expressed in CHO cells co-expressing G-alpha16 incubated for 24 hrs by fluo-4 AM dye based whole-ce...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2XJ1PubMed