Compile Data Set for Download or QSAR
Found 16 Enz. Inhib. hit(s) with Target = 'Carbonic anhydrase 1' and Ligand = 'BDBM10874'
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Università degli Studi

Curated by ChEMBL
LigandPNGBDBM10874(6-hydroxy-1,3-benzothiazole-2-sulfonamide | CHEMBL...)copy SMILEScopy InChI
Affinity DataKi:  55nMAssay Description:Inhibitory activity against human carbonic anhydrase I (CA1)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22806T7PubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Università degli Studi

Curated by ChEMBL
LigandPNGBDBM10874(6-hydroxy-1,3-benzothiazole-2-sulfonamide | CHEMBL...)copy SMILEScopy InChI
Affinity DataKi:  55nMAssay Description:Inhibition of human CA1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z761VPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Università degli Studi

Curated by ChEMBL
LigandPNGBDBM10874(6-hydroxy-1,3-benzothiazole-2-sulfonamide | CHEMBL...)copy SMILEScopy InChI
Affinity DataKi:  55nMAssay Description:Inhibitory activity against Human carbonic anhydrase IMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N29XN9PubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Università degli Studi

Curated by ChEMBL
LigandPNGBDBM10874(6-hydroxy-1,3-benzothiazole-2-sulfonamide | CHEMBL...)copy SMILEScopy InChI
Affinity DataKi:  55nMAssay Description:Inhibitory activity against human recombinant carbonic anhydrase I (CA1)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1XXCPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Università degli Studi

Curated by ChEMBL
LigandPNGBDBM10874(6-hydroxy-1,3-benzothiazole-2-sulfonamide | CHEMBL...)copy SMILEScopy InChI
Affinity DataKi:  55nMAssay Description:Inhibition of human cloned Carbonic anhydrase I (hCA I,cytosolic form)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67HMKPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Università degli Studi

Curated by ChEMBL
LigandPNGBDBM10874(6-hydroxy-1,3-benzothiazole-2-sulfonamide | CHEMBL...)copy SMILEScopy InChI
Affinity DataKi:  55nMAssay Description:Inhibition of cloned isozyme, human carbonic anhydrase IMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5GJQPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Università degli Studi

Curated by ChEMBL
LigandPNGBDBM10874(6-hydroxy-1,3-benzothiazole-2-sulfonamide | CHEMBL...)copy SMILEScopy InChI
Affinity DataKi:  55nMAssay Description:Inhibitory activity against human cloned carbonic anhydrase isozyme I by esterase assay method.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6KXVPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Università degli Studi

Curated by ChEMBL
LigandPNGBDBM10874(6-hydroxy-1,3-benzothiazole-2-sulfonamide | CHEMBL...)copy SMILEScopy InChI
Affinity DataKi:  95nMAssay Description:Inhibition of human recombinant CA1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM598PPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Università degli Studi

Curated by ChEMBL
LigandPNGBDBM10874(6-hydroxy-1,3-benzothiazole-2-sulfonamide | CHEMBL...)copy SMILEScopy InChI
Affinity DataKi:  95nMAssay Description:Ki value against human carbonic anhydrase I (hCA I)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29887RZPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Università degli Studi

Curated by ChEMBL
LigandPNGBDBM10874(6-hydroxy-1,3-benzothiazole-2-sulfonamide | CHEMBL...)copy SMILEScopy InChI
Affinity DataKi:  95nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5P89PubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Università degli Studi

Curated by ChEMBL
LigandPNGBDBM10874(6-hydroxy-1,3-benzothiazole-2-sulfonamide | CHEMBL...)copy SMILEScopy InChI
Affinity DataKi:  95nMpH: 7.5Assay Description:Inhibition of human recombinant carbonic anhydrase 1 at pH 7.5 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6JRWPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Università degli Studi

Curated by ChEMBL
LigandPNGBDBM10874(6-hydroxy-1,3-benzothiazole-2-sulfonamide | CHEMBL...)copy SMILEScopy InChI
Affinity DataKi:  95nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase I by spectrophotometry at pH 7.5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53M44PubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Università degli Studi

Curated by ChEMBL
LigandPNGBDBM10874(6-hydroxy-1,3-benzothiazole-2-sulfonamide | CHEMBL...)copy SMILEScopy InChI
Affinity DataKi:  95nMAssay Description:Inhibition of recombinant human carbonic anhydrase-1 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB83QGPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Università degli Studi

Curated by ChEMBL
LigandPNGBDBM10874(6-hydroxy-1,3-benzothiazole-2-sulfonamide | CHEMBL...)copy SMILEScopy InChI
Affinity DataKi:  95nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2TQBPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Università degli Studi

Curated by ChEMBL
LigandPNGBDBM10874(6-hydroxy-1,3-benzothiazole-2-sulfonamide | CHEMBL...)copy SMILEScopy InChI
Affinity DataKi:  95nMAssay Description:Inhibition of human recombinant cytosolic isozyme CA I by stopped-flow CO2 hydrase methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5NNHPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Università degli Studi

Curated by ChEMBL
LigandPNGBDBM10874(6-hydroxy-1,3-benzothiazole-2-sulfonamide | CHEMBL...)copy SMILEScopy InChI
Affinity DataKi:  2.10E+4nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ3463PubMed